The average train between Sestri Ponente and Pisa takes 3h 11m and the fastest train takes 2h 6m. There is a train service every few hours from Sestri Ponente to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Sestri Ponente and Pisa. The earliest departure is at 5:24 AM in the morning, and the last departure from Sestri Ponente is at 10:12 PM which arrives into Pisa at 7:04 AM. All services require a transfer, and take on average 3h 11m. The schedules shown below are for the next available departures.

2h 40m • 1 change

3h 6m • 1 change

2h 44m • 1 change

2h 53m • 1 change

2h 6m • 1 change

2h 57m • 1 change

3h 2m • 1 change

2h 42m • 1 change

2h 6m • 1 change

2h 57m • 1 change

3h 2m • 1 change

2h 42m • 1 change

2h 6m • 1 change

2h 57m • 1 change

3h 2m • 1 change

2h 42m • 1 change
Want to know about travelling from Sestri Ponente to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sestri Ponente to Pisa. However, there are services departing from Sestri Ponente station and arriving at Pisa station via Pisa Centrale. The journey, including transfers, takes approximately 3h 11m.
Sestri Ponente to Pisa train services, operated by Trenitalia, depart from Genova P.Za Principe station.
Sestri Ponente to Pisa train services, operated by Trenitalia, arrive at Pisa Centrale station.
Book your Sestri Ponente to Pisa train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Sestri Ponente and Pisa is 147.5 km. The road distance is 168 km.
Trenitalia Frecce operates a train from Genova P.Za Principe to Pisa Centrale every 2 hours. Tickets cost €24–50 and the journey takes 1h 59m. Two other operators also service this route.