The average train between Sezze and Florence takes 3h 29m and the fastest train takes 3h 3m. There is a train service every few hours from Sezze to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Sezze and Florence. The earliest departure is at 4:51 AM at night, and the last departure from Sezze is at 10:49 PM which arrives into Florence at 6:46 AM. All services require a transfer, and take on average 3h 29m. The schedules shown below are for the next available departures.

3h 17m • 1 change

3h 15m • 1 change

3h 28m • 1 change

3h 17m • 1 change

3h 20m • 1 change

3h 28m • 1 change

3h 19m • 1 change

3h 19m • 1 change

3h 20m • 1 change

3h 36m • 1 change

3h 16m • 1 change

3h 3m • 1 change
Want to know about travelling from Sezze to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sezze to Florence. However, there are services departing from Sezze station and arriving at Florence station via Roma Termini. The journey, including transfers, takes approximately 3h 29m.
Sezze to Florence train services, operated by Trenitalia, depart from Sezze Romano station.
Sezze to Florence train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Sezze to Florence train tickets online with Trenitalia and Trenitalia Frecce.
The distance between Sezze and Florence is 293.7 km. The road distance is 331 km.
You can take a train from Sezze Romano to Firenze S.M.N. via Roma Termini in around 2h 44m.