The average train between Sezze and Milan takes 5h and the fastest train takes 3h 57m. There is a train service every few hours from Sezze to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Sezze and Milan. The earliest departure is at 4:51 AM at night, and the last departure from Sezze is at 10:49 PM which arrives into Milan at 9:20 AM. All services require a transfer, and take on average 5h. The schedules shown below are for the next available departures.

4h 16m • 1 change

4h 46m • 1 change
Arrives next day

10h 31m • 1 change

4h 54m • 1 change

4h 27m • 1 change

4h 13m • 1 change

5h 1m • 1 change

4h 54m • 1 change

4h 27m • 1 change

4h 13m • 1 change

5h 1m • 1 change

4h 54m • 1 change

4h 27m • 1 change

5h 7m • 1 change

5h 1m • 1 change
Want to know about travelling from Sezze to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sezze to Milan. However, there are services departing from Sezze station and arriving at Milan station via Roma Termini. The journey, including transfers, takes approximately 5h.
Sezze to Milan train services, operated by Trenitalia, depart from Sezze Romano station.
Sezze to Milan train services, operated by Trenitalia, arrive at Milano Centrale station.
Book your Sezze to Milan train tickets online with Trenitalia and ItaloTreno.
The distance between Sezze and Milan is 540.1 km. The road distance is 650 km.
You can take a train from Sezze Romano to Milano Centrale via Roma Termini in around 4h 13m.