The average train between Sicily and Isernia takes 12h 46m and the fastest train takes 11h 52m. The train service runs several times per day from Sicily to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Sicily and Isernia. The earliest departure is at 2:46 AM at night, and the last departure from Sicily is at 9:30 AM which arrives into Isernia at 9:43 PM. All services require a transfer at Palermo Centrale and take an average of 12h 46m. The schedules shown below are for the next available departures.
Want to know about travelling from Sicily to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sicily to Isernia. However, there are services departing from Sicily station and arriving at Isernia station via Napoli Centrale. The journey, including transfers, takes approximately 12h 46m.
Sicily to Isernia train services, operated by Trenitalia, depart from Palermo Centrale station.
Sicily to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Sicily to Isernia train tickets online with Trenitalia and Trenitalia Intercity.
The distance between Sicily and Isernia is 445.7 km. The road distance is 788 km.
You can take a train from Palermo Notarbartolo to Isernia via Palermo Centrale and Napoli Centrale in around 13h 28m.
