Siena Station to Milano Centrale Station Trains

Siena Station to Milano Centrale Station trains

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Trip Overview

The average train between Siena Station and Milano Centrale Station takes 5h 4m and the fastest train takes 3h 35m. There is a train service every few hours from Siena Station to Milano Centrale Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 4m
Duration: 397 km
Distance: €59
Average price: Hourly
Frequency

Train

best

Take the train from Siena to Firenze S.M.N.train Re / ...
Take the train from Firenze S.M.N. to Milano Centraletrain Fr

3h 47m

€42–109

Siena Station to Milano Centrale Station train times

Trains run hourly between Siena Station and Milano Centrale Station. The earliest departure is at 6:25 AM in the morning, and the last departure from Siena Station is at 9:40 PM which arrives into Milano Centrale Station at 9:05 AM. All services require a transfer, and take on average 5h 4m. The schedules shown below are for the next available departures.

Departing Saturday, August 22, 2026

6:25 AM → 10:00 AM
3h 35m • 1 change
6:36 AM → 11:05 AM
4h 29m • 1 change
7:02 AM → 12:05 PM
5h 3m • 1 change
8:48 AM → 1:05 PM
4h 17m • 1 change
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Departing Sunday, August 23, 2026

6:36 AM → 11:05 AM
4h 29m • 1 change
7:15 AM → 12:05 PM
4h 50m • 1 change
8:48 AM → 1:05 PM
4h 17m • 1 change
12:18 PM → 5:05 PM
4h 47m • 1 change
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Departing Monday, August 24, 2026

6:25 AM → 10:00 AM
3h 35m • 1 change
6:36 AM → 11:05 AM
4h 29m • 1 change
7:02 AM → 12:05 PM
5h 3m • 1 change
8:48 AM → 1:05 PM
4h 17m • 1 change
Show more

Departing Tuesday, August 25, 2026

6:25 AM → 10:00 AM
3h 35m • 1 change
6:36 AM → 11:05 AM
4h 29m • 1 change
7:02 AM → 12:05 PM
5h 3m • 1 change
8:48 AM → 1:05 PM
4h 17m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Siena Station to Milano Centrale Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.