Siena, Stazione FS to Rome Trains

Siena, Stazione FS to Rome trains

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Trip Overview

The average train between Siena, Stazione FS and Rome takes 3h 51m and the fastest train takes 3h 8m. There is a train service every few hours from Siena, Stazione FS to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 51m
Duration: 354 km
Distance: €48
Average price: Hourly
Frequency

Train

best

Take the train from Siena to Firenze S.M.N.train Re / ...
Take the train from Firenze S.M.N. to Roma Terminitrain Fr

3h 25m

€39–75

Siena, Stazione FS to Rome train times

Trains run hourly between Siena, Stazione FS and Rome. The earliest departure is at 6:25 AM in the morning, and the last departure from Siena, Stazione FS is at 9:40 PM which arrives into Rome at 7:49 AM. All services require a transfer, and take on average 3h 51m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

7:18 PM → 11:10 PM
3h 52m • 1 change
8:18 PM → 11:54 PM
3h 36m • 1 change
9:40 PM → 7:49 AM
Arrives next day
10h 9m • 1 change

Departing Wednesday, November 4, 2026

6:25 AM → 9:33 AM
3h 8m • 1 change
6:36 AM → 10:25 AM
3h 49m • 1 change
7:02 AM → 10:49 AM
3h 47m • 1 change
8:18 AM → 11:49 AM
3h 31m • 1 change
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Departing Thursday, November 5, 2026

6:25 AM → 9:33 AM
3h 8m • 1 change
6:36 AM → 10:25 AM
3h 49m • 1 change
7:02 AM → 10:49 AM
3h 47m • 1 change
8:18 AM → 11:49 AM
3h 31m • 1 change
Show more

Departing Friday, November 6, 2026

6:25 AM → 9:33 AM
3h 8m • 1 change
6:36 AM → 10:25 AM
3h 49m • 1 change
7:02 AM → 10:49 AM
3h 47m • 1 change
8:18 AM → 11:49 AM
3h 31m • 1 change
Show more

Departing Saturday, November 7, 2026

6:25 AM → 9:33 AM
3h 8m • 1 change
6:36 AM → 10:25 AM
3h 49m • 1 change
7:02 AM → 10:49 AM
3h 47m • 1 change
8:18 AM → 11:49 AM
3h 31m • 1 change
Show more

Departing Sunday, November 8, 2026

6:36 AM → 9:49 AM
3h 13m • 1 change
7:15 AM → 10:49 AM
3h 34m • 1 change
8:18 AM → 11:49 AM
3h 31m • 1 change
8:48 AM → 12:15 PM
3h 27m • 1 change
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Departing Monday, November 9, 2026

6:25 AM → 9:33 AM
3h 8m • 1 change
6:36 AM → 10:25 AM
3h 49m • 1 change
7:02 AM → 10:49 AM
3h 47m • 1 change
8:18 AM → 11:49 AM
3h 31m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Siena, Stazione FS to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.