The average train between Siena and Casale Monferrato takes 8h 30m and the fastest train takes 6h 55m. The train service runs several times per day from Siena to Casale Monferrato. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Siena and Casale Monferrato. The earliest departure is at 7:02 AM in the morning, and the last departure from Siena is at 7:18 PM which arrives into Casale Monferrato at 9:28 AM. All services require a transfer at Firenze S.M.N. and take an average of 8h 30m. The schedules shown below are for the next available departures.



6h 58m • 3 changes
Arrives next day



11h 27m • 3 changes
Arrives next day



14h 10m • 3 changes



7h 3m • 3 changes



6h 55m • 3 changes



7h 22m • 3 changes



6h 58m • 3 changes



7h 3m • 3 changes



6h 55m • 3 changes



7h 22m • 3 changes



6h 58m • 3 changes
Want to know about travelling from Siena to Casale Monferrato? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Siena to Casale Monferrato. However, there are services departing from Siena station and arriving at Casale Monferrato station via Firenze S.M.N.. The journey, including transfers, takes approximately 8h 30m.
Siena to Casale Monferrato train services, operated by Trenitalia, depart from Siena station.
Siena to Casale Monferrato train services, operated by Trenitalia, arrive at Mortara station.
Book your Siena to Casale Monferrato train tickets online with Trenitalia, Trenitalia Frecce and Trenord.
The distance between Siena and Casale Monferrato is 305.5 km. The road distance is 466 km.
You can take a train from Siena to Casale Monferrato via Firenze S.M.N., Milan Rogoredo, and Mortara in around 6h 38m.