The average train between Siena and Lake Iseo takes 6h 41m and the fastest train takes 4h 48m. The train service runs several times per day from Siena to Lake Iseo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Siena and Lake Iseo. The earliest departure is at 6:36 AM in the morning, and the last departure from Siena is at 6:18 PM which arrives into Lake Iseo at 6:37 AM. All services require a transfer at Firenze S.M.N. and take an average of 6h 41m. The schedules shown below are for the next available departures.



5h • 3 changes


4h 48m • 3 changes


5h 19m • 3 changesArrives next day



13h 18m • 3 changes


5h • 3 changes


4h 48m • 3 changes


7h 19m • 3 changesArrives next day



12h 19m • 3 changes


5h • 3 changes


4h 48m • 3 changes


5h 19m • 3 changes


6h 19m • 3 changes


5h • 3 changes


4h 48m • 3 changes


5h 19m • 3 changes


6h 19m • 3 changes


5h • 3 changes


4h 48m • 3 changes


5h 19m • 3 changes


6h 19m • 3 changesWant to know about travelling from Siena to Lake Iseo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Siena to Lake Iseo. However, there are services departing from Siena station and arriving at Lake Iseo station via Firenze S.M.N.. The journey, including transfers, takes approximately 6h 41m.
Siena to Lake Iseo train services, operated by Trenitalia, depart from Siena station.
Siena to Lake Iseo train services, operated by Trenitalia, arrive at Brescia station.
Book your Siena to Lake Iseo train tickets online with Trenitalia, Trenitalia Frecce and 2 other operators.
The distance between Siena and Lake Iseo is 284.9 km. The road distance is 395 km.
You can take a train from Siena to Sulzano via Firenze S.M.N., Verona Porta Nuova, and Brescia in around 6h 6m.