The average train between Sistine Chapel and Pisa takes 3h 31m and the fastest train takes 2h 55m. There is an hourly train service from Sistine Chapel to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Sistine Chapel and Pisa. The earliest departure is at 6:00 AM in the morning, and the last departure from Sistine Chapel is at 11:37 PM which arrives into Pisa at 7:51 AM. All services require a transfer at Cavalleggeri/Fornaci and take an average of 3h 31m. The schedules shown below are for the next available departures.


3h 27m • 2 changes


3h 38m • 2 changes


3h 21m • 2 changes


3h 29m • 2 changes


3h 27m • 2 changes


3h 25m • 2 changes


3h 23m • 2 changes


3h 19m • 2 changes


3h 27m • 2 changes


3h 25m • 2 changes


3h 23m • 2 changes


3h 19m • 2 changes
Want to know about travelling from Sistine Chapel to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sistine Chapel to Pisa. However, there are services departing from Sistine Chapel station and arriving at Pisa station via Pisa Centrale. The journey, including transfers, takes approximately 3h 31m.
Sistine Chapel to Pisa train services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma Termini station.
Sistine Chapel to Pisa train services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Pisa Centrale station.
The distance between Sistine Chapel and Pisa is 261.3 km. The road distance is 342 km.
Trenitalia Frecce operates a train from Roma Termini to Pisa Centrale every 4 hours. Tickets cost €45–100 and the journey takes 2h 27m. Two other operators also service this route.