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Sistine Chapel to Pisa trains

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Trip Overview

The average train between Sistine Chapel and Pisa takes 7h and the fastest train takes 2h 44m. The train service runs several times per day from Sistine Chapel to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h
Duration
345 km
Distance
€57
Average price
Twice daily
Frequency

Sistine Chapel to Pisa train times

Trains run twice daily between Sistine Chapel and Pisa. The earliest departure is at 7:44 PM in the evening, and the last departure from Sistine Chapel is at 9:45 PM which arrives into Pisa at 8:45 AM. All services require a transfer at Roma S. Pietro and take an average of 7h. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    TrenitaliaTrenitalia Frecce2h 44m • 1 change
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    Arrives next day

    TrenitaliaTrenitalia Frecce11h 19m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    TrenitaliaTrenitalia Frecce2h 44m • 1 change
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    Arrives next day

    TrenitaliaTrenitalia Frecce11h 19m • 1 change

Departing Wednesday, November 4, 2026

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    TrenitaliaTrenitalia Frecce2h 44m • 1 change
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    Arrives next day

    TrenitaliaTrenitalia Frecce11h 19m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    TrenitaliaTrenitalia Frecce2h 44m • 1 change
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    Arrives next day

    TrenitaliaTrenitalia Frecce11h 19m • 1 change

Departing Friday, November 6, 2026

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    TrenitaliaTrenitalia Frecce2h 44m • 1 change
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    Arrives next day

    TrenitaliaTrenitalia Frecce11h 19m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    TrenitaliaTrenitalia Frecce11h • 1 change

Departing Sunday, November 8, 2026

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    TrenitaliaTrenitalia Frecce2h 56m • 1 change

Frequently asked questions

Want to know about travelling from Sistine Chapel to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Sistine Chapel to Pisa.ExpandLaunch map view
  • Distance: 344.9 km
  • Duration: 7h

What companies run services between Sistine Chapel, Vatican City and Pisa, Italy?

Trenitalia Frecce operates a train from Roma Tiburtina to Pisa Centrale twice daily. Tickets cost €45–80 and the journey takes 2h 18m.

Operators