The average train between Skokie and St. Louis takes 6h 41m and the fastest train takes 5h 51m. The train service runs several times per day from Skokie to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Skokie and St. Louis. The earliest departure is at 5:50 AM in the morning, and the last departure from Skokie is at 11:45 PM which arrives into St. Louis at 12:01 PM. All services require a transfer, and take on average 6h 41m. The schedules shown below are for the next available departures.

6h 11m • 1 change

5h 51m • 1 change

6h 29m • 1 change

6h 27m • 1 change

6h 11m • 1 change

5h 51m • 1 change

6h 29m • 1 change

6h 27m • 1 change

6h 11m • 1 change

5h 51m • 1 change

6h 29m • 1 change

6h 27m • 1 change

6h 11m • 1 change

5h 51m • 1 change

6h 29m • 1 change

6h 27m • 1 change

7h • 1 change

7h 34m • 1 change

6h 32m • 1 change
Arrives next day

6h 18m • 1 change

7h • 1 change

7h 34m • 1 change

6h 32m • 1 change
Arrives next day

6h 18m • 1 change

6h 11m • 1 change

5h 51m • 1 change

6h 29m • 1 change

6h 27m • 1 change
Want to know about travelling from Skokie to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Skokie to St. Louis. However, there are services departing from Skokie station and arriving at St. Louis station via St. Louis. The journey, including transfers, takes approximately 6h 41m.
Skokie to St. Louis train services, operated by Metra, depart from Chicago Union Station.
Skokie to St. Louis train services, operated by Metra, arrive at St. Louis station.
The distance between Skokie and St. Louis is 432.5 km. The road distance is 471 km.
Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $90–190 and the journey takes 4h 46m.