The average train between Slough and Darwen takes 4h 43m and the fastest train takes 4h 2m. There is a train service every few hours from Slough to Darwen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Slough and Darwen. The earliest departure is at 5:22 AM in the morning, and the last departure from Slough is at 11:21 PM which arrives into Darwen at 9:25 AM. All services require a transfer at Tottenham Court Road Station and take an average of 4h 43m. The schedules shown below are for the next available departures.




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4h 4m • 4 changesWant to know about travelling from Slough to Darwen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Darwen. However, there are services departing from London Euston station and arriving at Manchester Piccadilly station via Manchester Piccadilly station. The journey, including transfers, takes approximately 4h 43m.
Slough to Darwen train services, operated by Avanti West Coast, depart from London Euston station.
Slough to Darwen train services, operated by Avanti West Coast, arrive at Manchester Piccadilly station.
Book your Slough to Darwen train tickets online with Omio.
The distance between Slough and Darwen is 274.1 km. The road distance is 321 km.
Avanti West Coast operates a train from London Euston to Manchester Piccadilly every 30 minutes. Tickets cost £60–100 and the journey takes 2h 12m.