The average train between Slough and Holmes Chapel takes 3h 23m and the fastest train takes 2h 42m. There is an hourly train service from Slough to Holmes Chapel. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Slough and Holmes Chapel. The earliest departure is at 5:38 AM in the morning, and the last departure from Slough is at 11:21 PM which arrives into Holmes Chapel at 7:57 AM. All services require a transfer at Tottenham Court Road Station and take an average of 3h 23m. The schedules shown below are for the next available departures.



3h 30m • 3 changes
Arrives next day



9h 4m • 3 changes
Arrives next day



8h 36m • 3 changes



2h 49m • 3 changes



2h 51m • 3 changes



3h 12m • 3 changes



2h 42m • 3 changes



2h 49m • 3 changes



2h 51m • 3 changes



3h 12m • 3 changes



2h 42m • 3 changes
Want to know about travelling from Slough to Holmes Chapel? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Holmes Chapel. However, there are services departing from Slough station and arriving at Holmes Chapel station via Tottenham Court Rd. The journey, including transfers, takes approximately 3h 23m.
Slough to Holmes Chapel train services, operated by Elizabeth Line (TfL), depart from Slough station.
Slough to Holmes Chapel train services, operated by Elizabeth Line (TfL), arrive at Crewe station.
Book your Slough to Holmes Chapel train tickets online with Elizabeth Line (TfL), London Underground (Tube) and 2 other operators.
The distance between Slough and Holmes Chapel is 222.9 km. The road distance is 301 km.
You can take a train from Slough to Holmes Chapel via Tottenham Court Road Station, Tottenham Court Road station, Euston station, London Euston, and Crewe in around 3h 6m.