The average train between Slough and Lyon takes 6h 49m and the fastest train takes 5h 48m. The train service runs several times per day from Slough to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Slough and Lyon. The earliest departure is at 5:22 AM in the morning, and the last departure from Slough is at 6:51 PM which arrives into Lyon at 8:40 AM. All services require a transfer at Farringdon Without and take an average of 6h 49m. The schedules shown below are for the next available departures.




6h 48m • 4 changes




6h 49m • 4 changes




7h 20m • 4 changes




6h 58m • 4 changes




6h 48m • 4 changes




6h 49m • 4 changes




7h 20m • 4 changes




6h 58m • 4 changes




6h 48m • 4 changes




6h 49m • 4 changes




7h 20m • 4 changes




6h 58m • 4 changes




6h 48m • 4 changes




6h 49m • 4 changes




7h 20m • 4 changes




6h 58m • 4 changes
Want to know about travelling from Slough to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Lyon. However, there are services departing from Slough station and arriving at Lyon station via Paris Nord. The journey, including transfers, takes approximately 6h 49m.
Slough to Lyon train services, operated by Elizabeth Line (TfL), depart from London St Pancras Intl station.
Slough to Lyon train services, operated by Elizabeth Line (TfL), arrive at Lyon Part Dieu station.
Book your Slough to Lyon train tickets online with Elizabeth Line (TfL), Thameslink and 4 other operators.
The distance between Slough and Lyon is 754.7 km. The road distance is 919 km.
You can take a train from Slough to Lyon Part Dieu via Farringdon Without, Farringdon, London St Pancras Intl, Paris Nord, and Paris Gare De Lyon in around 6h 36m.