The average train between Slough and Lyon takes 7h 6m and the fastest train takes 5h 48m. The train service runs several times per day from Slough to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Slough and Lyon. The earliest departure is at 5:22 AM in the morning, and the last departure from Slough is at 11:21 PM which arrives into Lyon at 11:56 AM. All services require a transfer at Farringdon Without and take an average of 7h 6m. The schedules shown below are for the next available departures.




5h 48m • 4 changes



5h 49m • 4 changes



6h 20m • 4 changes



5h 58m • 4 changes



5h 48m • 4 changes



5h 49m • 4 changes



6h 20m • 4 changes



5h 58m • 4 changes



5h 48m • 4 changes



5h 49m • 4 changes



6h 20m • 4 changes



5h 58m • 4 changes



5h 48m • 4 changes



5h 49m • 4 changes



6h 20m • 4 changes



5h 58m • 4 changes



5h 48m • 4 changes



5h 49m • 4 changes



6h 20m • 4 changes



5h 58m • 4 changes



6h 34m • 4 changes



6h 5m • 4 changes



6h 35m • 4 changes



6h 35m • 4 changes



6h 6m • 4 changes



5h 57m • 4 changes



6h 35m • 4 changes



6h 3m • 4 changesWant to know about travelling from Slough to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Lyon. However, there are services departing from London St Pancras Intl station and arriving at Lyon Part Dieu station via Paris Nord station. The journey, including transfers, takes approximately 7h 6m.
Slough to Lyon train services, operated by Eurostar, depart from London St Pancras Intl station.
Slough to Lyon train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Book your Slough to Lyon train tickets online with Omio.
The distance between Slough and Lyon is 754.7 km.
You can take a train from Slough to Lyon Part Dieu via Farringdon Without, Farringdon, London St Pancras Intl, Paris Nord, and Paris Gare De Lyon in around 6h 32m.