Slough to Manchester Trains

Slough to Manchester trains

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Trip Overview

The average train between Slough and Manchester takes 3h 18m and the fastest train takes 2h 56m. The train runs at least 2 times per hour from Slough to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 18m
Duration: 204 mi
Distance: £95
Average price: Every 30 minutes
Frequency

Train via London

best

Take the train from Slough to Tottenham Court Rdtrain Elizabeth
Take the train from London Euston to Manchester Piccadillytrain London Euston - Manchester Piccadilly

3h 14m

£77–131

Slough to Manchester train times

Trains run every 30 minutes between Slough and Manchester. The earliest departure is at 5:38 AM in the morning, and the last departure from Slough is at 11:21 PM which arrives into Manchester at 8:25 AM. All services require a transfer at Tottenham Court Road Station and take an average of 3h 18m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

4:51 PM → 8:05 PM
3h 14m • 2 changes
5:21 PM → 8:19 PM
2h 58m • 2 changes
5:51 PM → 9:05 PM
3h 14m • 2 changes
6:21 PM → 9:19 PM
2h 58m • 2 changes
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Departing Sunday, November 1, 2026

9:16 AM → 1:02 PM
3h 46m • 2 changes
10:21 AM → 1:49 PM
3h 28m • 2 changes
10:51 AM → 2:19 PM
3h 28m • 2 changes
11:21 AM → 2:44 PM
3h 23m • 2 changes
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Departing Monday, November 2, 2026

5:38 AM → 8:45 AM
3h 7m • 2 changes
5:53 AM → 9:05 AM
3h 12m • 2 changes
6:08 AM → 9:19 AM
3h 11m • 2 changes
6:36 AM → 9:44 AM
3h 8m • 2 changes
Show more

Departing Tuesday, November 3, 2026

5:38 AM → 8:45 AM
3h 7m • 2 changes
5:53 AM → 9:05 AM
3h 12m • 2 changes
6:08 AM → 9:19 AM
3h 11m • 2 changes
6:36 AM → 9:44 AM
3h 8m • 2 changes
Show more

Departing Wednesday, November 4, 2026

5:38 AM → 8:45 AM
3h 7m • 2 changes
5:53 AM → 9:05 AM
3h 12m • 2 changes
6:08 AM → 9:19 AM
3h 11m • 2 changes
6:36 AM → 9:44 AM
3h 8m • 2 changes
Show more

Departing Thursday, November 5, 2026

5:38 AM → 8:45 AM
3h 7m • 2 changes
5:53 AM → 9:05 AM
3h 12m • 2 changes
6:08 AM → 9:19 AM
3h 11m • 2 changes
6:36 AM → 9:44 AM
3h 8m • 2 changes
Show more

Departing Friday, November 6, 2026

5:38 AM → 8:45 AM
3h 7m • 2 changes
5:53 AM → 9:05 AM
3h 12m • 2 changes
6:08 AM → 9:19 AM
3h 11m • 2 changes
6:36 AM → 9:44 AM
3h 8m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Slough to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.