The average train between Slough and Southport takes 4h 58m and the fastest train takes 3h 45m. There is a train service every few hours from Slough to Southport. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Slough and Southport. The earliest departure is at 6:36 AM in the morning, and the last departure from Slough is at 11:21 PM which arrives into Southport at 8:43 AM. All services require a transfer at Tottenham Court Road Station and take an average of 4h 58m. The schedules shown below are for the next available departures.



3h 53m • 3 changes



3h 48m • 3 changes



4h 9m • 3 changes



4h 2m • 3 changes



3h 54m • 3 changes



3h 49m • 3 changes



3h 45m • 3 changes



3h 47m • 3 changes



3h 54m • 3 changes



3h 49m • 3 changes



3h 45m • 3 changes



3h 47m • 3 changes



3h 54m • 3 changes



3h 49m • 3 changes



3h 45m • 3 changes



3h 47m • 3 changes
Want to know about travelling from Slough to Southport? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Southport. However, there are services departing from Slough station and arriving at Southport station via Tottenham Court Rd. The journey, including transfers, takes approximately 4h 58m.
Slough to Southport train services, operated by Elizabeth Line (TfL), depart from Slough station.
Slough to Southport train services, operated by Elizabeth Line (TfL), arrive at Wigan North Western station.
Book your Slough to Southport train tickets online with Elizabeth Line (TfL), London Underground (Tube) and 2 other operators.
The distance between Slough and Southport is 288.1 km. The road distance is 373 km.
You can take a train from Slough to Southport via Tottenham Court Road Station, Tottenham Court Road station, Euston station, London Euston, Wigan North Western, and Wigan Wallgate in around 4h 2m.