The average train between Slough and St James's Square takes 39 min and the fastest train takes 28 min. The train runs at least 2 times per hour from Slough to St James's Square. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 30 minutes between Slough and St James's Square. The earliest departure is at 4:59 AM at night, and the last departure from Slough is at 10:38 PM which arrives into St James's Square at 11:27 PM. All services require a transfer at London Paddington and take an average of 39 min. The schedules shown below are for the next available departures.

56 min • 1 change

47 min • 1 change

47 min • 1 change

39 min • 1 change
Want to know about travelling from Slough to St James's Square? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to St James's Square. However, there are services departing from Slough station and arriving at St James's Square station via London Paddington. The journey, including transfers, takes approximately 39 min.
Slough to St James's Square train services, operated by Elizabeth Line (TfL), depart from Slough station.
Slough to St James's Square train services, operated by Elizabeth Line (TfL), arrive at Piccadilly Circus station.
Book your Slough to St James's Square train tickets online with Elizabeth Line (TfL), London Underground (Tube) and Great Western Railway (GWR).
The distance between Slough and St James's Square is 31.9 km. The road distance is 34 km.
Elizabeth Line (TfL) operates a train from Slough to Tottenham Court Rd every 30 minutes. Tickets cost £15–30 and the journey takes 40 min.