The average train between Southampton and Mainz takes 9h and the fastest train takes 7h 14m. The train service runs several times per day from Southampton to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Southampton and Mainz. The earliest departure is at 4:49 AM at night, and the last departure from Southampton is at 9:58 PM which arrives into Mainz at 1:44 PM. All services require a transfer at London Waterloo Station and take an average of 9h. The schedules shown below are for the next available departures.




7h 55m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 55m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 55m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 55m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 55m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changes



7h 44m • 4 changesWant to know about travelling from Southampton to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Southampton to Mainz. However, there are services departing from Southampton Central station and arriving at Frankfurt station via London Waterloo station and Brussel-Zuid / Bruxelles-Midi station. The journey, including transfers, takes approximately 9h.
Southampton to Mainz train services, operated by South Western Railway, depart from Southampton Central station.
Southampton to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Book your Southampton to Mainz train tickets online with Omio.
The distance between Southampton and Mainz is 692.8 km.
You can take a train from Southampton Central to Mainz, Römisches Theater via London Waterloo Station, Waterloo station, Euston station, London St Pancras Intl, Brussels-Midi, Bruxelles Midi, and Frankfurt in around 9h 3m.