The average train between Southampton and Manchester Airport (MAN) takes 4h 42m and the fastest train takes 4h 38m. There is a train service every few hours from Southampton to Manchester Airport (MAN). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Southampton and Manchester Airport (MAN). The earliest departure is at 5:15 AM in the morning, and the last departure from Southampton is at 7:15 PM which arrives into Manchester Airport (MAN) at 11:53 PM. All services require a transfer, and take on average 4h 42m. The schedules shown below are for the next available departures.

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Want to know about travelling from Southampton to Manchester Airport (MAN)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Southampton to Manchester Airport (MAN). However, there are services departing from Southampton station and arriving at Manchester Airport (MAN) station via Manchester Piccadilly. The journey, including transfers, takes approximately 4h 42m.
Southampton to Manchester Airport (MAN) train services, operated by Cross Country, depart from Southampton Central station.
Southampton to Manchester Airport (MAN) train services, operated by Cross Country, arrive at Manchester Piccadilly station.
Book your Southampton to Manchester Airport (MAN) train tickets online with Cross Country, Northern Trains Limited and Transport for Wales.
The distance between Southampton and Manchester Airport (MAN) is 280 km. The road distance is 380 km.
Cross Country operates a train from Southampton Central to Manchester Piccadilly hourly. Tickets cost £120–180 and the journey takes 4h 14m.