The average train between Southampton and Middlesex takes 1h 48m and the fastest train takes 1h 41m. There is a train service every few hours from Southampton to Middlesex. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Southampton and Middlesex. The earliest departure is at 5:15 AM in the morning, and the last departure from Southampton is at 8:15 PM which arrives into Middlesex at 9:56 PM. All services require a transfer at Reading and take an average of 1h 48m. The schedules shown below are for the next available departures.


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1h 54m • 2 changesWant to know about travelling from Southampton to Middlesex? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Southampton to Middlesex. However, there are services departing from Southampton station and arriving at Middlesex station via Reading. The journey, including transfers, takes approximately 1h 48m.
Southampton to Middlesex train services, operated by Cross Country, depart from Southampton Central station.
Southampton to Middlesex train services, operated by Cross Country, arrive at London Paddington station.
Book your Southampton to Middlesex train tickets online with Cross Country, Great Western Railway (GWR) and London Underground (Tube).
The distance between Southampton and Middlesex is 105.5 km. The road distance is 140 km.
You can take a train from Southampton Central to Harlesden station via Reading, London Paddington, and Paddington station in around 1h 41m.