The average train between Southampton and Uxbridge takes 1h 40m and the fastest train takes 1h 29m. There is a train service every few hours from Southampton to Uxbridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Southampton and Uxbridge. The earliest departure is at 5:15 AM in the morning, and the last departure from Southampton is at 8:15 PM which arrives into Uxbridge at 10:00 PM. All services require a transfer, and take on average 1h 40m. The schedules shown below are for the next available departures.

1h 30m • 1 change

1h 29m • 1 change

1h 30m • 1 change

1h 38m • 1 change

1h 30m • 1 change

1h 29m • 1 change

1h 30m • 1 change

1h 38m • 1 change

1h 45m • 1 change

1h 44m • 1 change

1h 45m • 1 change

1h 45m • 1 change
Want to know about travelling from Southampton to Uxbridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Southampton to Uxbridge. However, there are services departing from Southampton station and arriving at Uxbridge station via Reading. The journey, including transfers, takes approximately 1h 40m.
Southampton to Uxbridge train services, operated by Cross Country, depart from Southampton Central station.
Southampton to Uxbridge train services, operated by Cross Country, arrive at West Drayton station.
Book your Southampton to Uxbridge train tickets online with Cross Country and Elizabeth Line (TfL).
The distance between Southampton and Uxbridge is 96.3 km. The road distance is 111 km.
You can take a train from Southampton Central to West Drayton via Reading in around 1h 37m.