The average train between Southampton and Wilmslow takes 4h 38m and the fastest train takes 3h 58m. There is a train service every few hours from Southampton to Wilmslow. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Southampton and Wilmslow. The earliest departure is at 5:15 AM in the morning, and the last departure from Southampton is at 7:15 PM which arrives into Wilmslow at 8:24 AM. All services require a transfer, and take on average 4h 38m. The schedules shown below are for the next available departures.

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4h 9m • 1 changeWant to know about travelling from Southampton to Wilmslow? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Southampton to Wilmslow. However, there are services departing from Southampton Central station and arriving at Wilmslow station via Stafford station. The journey, including transfers, takes approximately 4h 38m.
Southampton to Wilmslow train services, operated by Cross Country, depart from Southampton Central station.
Southampton to Wilmslow train services, operated by Avanti West Coast, arrive at Wilmslow station.
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The distance between Southampton and Wilmslow is 275.4 km. The road distance is 324 km.
You can take a train from Southampton Central to Wilmslow via Stafford in around 4h 36m.