The average train between Speyer and Düsseldorf takes 3h 14m and the fastest train takes 2h 28m. The train service runs several times per day from Speyer to Düsseldorf. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Speyer and Düsseldorf. The earliest departure is at 4:23 AM at night, and the last departure from Speyer is at 11:35 PM which arrives into Düsseldorf at 6:32 AM. All services require a transfer, and take on average 3h 14m. The schedules shown below are for the next available departures.

2h 40m • 1 change

2h 28m • 1 change

2h 28m • 1 change

2h 28m • 1 change

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2h 28m • 1 change

2h 28m • 1 change

2h 28m • 1 change

2h 40m • 1 change

2h 28m • 1 change

2h 28m • 1 change

2h 28m • 1 change

2h 40m • 1 change

2h 28m • 1 change

2h 28m • 1 change

2h 28m • 1 change

2h 40m • 1 change

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2h 28m • 1 change

2h 28m • 1 change

4h 30m • 1 change

2h 28m • 1 change

2h 28m • 1 change

2h 28m • 1 change
Want to know about travelling from Speyer to Düsseldorf? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Speyer to Düsseldorf. However, there are services departing from Speyer station and arriving at Düsseldorf station via Düsseldorf Hbf. The journey, including transfers, takes approximately 3h 14m.
Speyer to Düsseldorf train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mannheim, Hauptbahnhof station.
Speyer to Düsseldorf train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Düsseldorf Hbf station.
Book your Speyer to Düsseldorf train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Speyer and Düsseldorf is 241.9 km. The road distance is 300 km.
Deutsche Bahn Intercity (DB IC) operates a train from Mannheim, Hauptbahnhof to Düsseldorf Hbf hourly. Tickets cost €50–220 and the journey takes 1h 46m. Nederlandse Spoorwegen (NS) also services this route once daily.