The average train between Speyer and Kassel takes 2h 46m and the fastest train takes 2h 40m. There is a train service every few hours from Speyer to Kassel. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Speyer and Kassel. The earliest departure is at 4:23 AM at night, and the last departure from Speyer is at 7:25 PM which arrives into Kassel at 10:11 PM. All services require a transfer, and take on average 2h 46m. The schedules shown below are for the next available departures.

2h 46m • 1 change

2h 42m • 1 change

2h 47m • 1 change

2h 44m • 1 change

2h 44m • 1 change

2h 58m • 1 change

2h 58m • 1 change

2h 42m • 1 change

3h 48m • 1 change

2h 55m • 1 change

2h 42m • 1 change

2h 46m • 1 change
Want to know about travelling from Speyer to Kassel? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Speyer to Kassel. However, there are services departing from Speyer station and arriving at Kassel station via Kassel Bahnhof Wilhelmshöhe. The journey, including transfers, takes approximately 2h 46m.
Speyer to Kassel train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mannheim, Hauptbahnhof station.
Speyer to Kassel train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Kassel Bahnhof Wilhelmshöhe station.
Book your Speyer to Kassel train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Speyer and Kassel is 234.5 km. The road distance is 292 km.
Deutsche Bahn Intercity (DB IC) operates a train from Mannheim, Hauptbahnhof to Kassel Bahnhof Wilhelmshöhe hourly. Tickets cost €45–210 and the journey takes 2h 8m.