The average train between Speyer and Leipzig takes 4h 52m and the fastest train takes 4h 7m. The train service runs several times per day from Speyer to Leipzig. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Speyer and Leipzig. The earliest departure is at 4:23 AM at night, and the last departure from Speyer is at 11:10 PM which arrives into Leipzig at 4:49 AM. All services require a transfer, and take on average 4h 52m. The schedules shown below are for the next available departures.

4h 44m • 1 change

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Arrives next day

5h 21m • 1 change

4h 56m • 1 change

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4h 56m • 1 change

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4h 56m • 1 change

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4h 34m • 1 change

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Want to know about travelling from Speyer to Leipzig? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Speyer to Leipzig. However, there are services departing from Speyer station and arriving at Leipzig station via Leipzig Hbf. The journey, including transfers, takes approximately 4h 52m.
Speyer to Leipzig train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mannheim, Hauptbahnhof station.
Speyer to Leipzig train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Leipzig Hbf station.
Book your Speyer to Leipzig train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Speyer and Leipzig is 358.5 km. The road distance is 472 km.
Deutsche Bahn Intercity (DB IC) operates a train from Mannheim, Hauptbahnhof to Leipzig Hbf every 2 hours. Tickets cost €80–350 and the journey takes 3h 40m. Österreichische Bundesbahnen also services this route twice daily.