The average train between Speyer and Prague takes 10h 21m and the fastest train takes 8h 54m. There is at least one train per day from Speyer to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Speyer and Prague. The earliest departure is at 5:27 AM in the morning, and the last departure from Speyer is at 11:35 PM which arrives into Prague at 12:21 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 10h 21m. The schedules shown below are for the next available departures.




8h 54m • 4 changes



9h 8m • 4 changes



8h 56m • 4 changes



8h 56m • 4 changesWant to know about travelling from Speyer to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Speyer to Prague. However, there are services departing from Mannheim, Hauptbahnhof station and arriving at Praha Hlavni Nadrazi station via Frankfurt station, Nürnberg Hbf station and Schwandorf station. The journey, including transfers, takes approximately 10h 21m.
Speyer to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Speyer to Prague train services, operated by Die Länderbahn, arrive at Praha Hlavni Nadrazi station.
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The distance between Speyer and Prague is 439 km. The road distance is 502 km.
You can take a train from Speyer, Hbf/ZOB to Praha Hlavni Nadrazi via Mannheim, Hauptbahnhof, Frankfurt, Nürnberg Hbf, and Schwandorf in around 9h 40m.