The average train between St. Louis and Buffalo takes 23h 49m and the fastest train takes 23h 37m. The train runs, on average, 6 times per week from St. Louis to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 6 times a week between St. Louis and Buffalo. The service departs St. Louis at 2:55 PM in the afternoon, which arrives into Buffalo at 15:40:00. All services require a transfer at Chicago Union Station and take an average of 23h 49m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from St. Louis to Buffalo. However, there are services departing from St. Louis station and arriving at Buffalo Depew Station via Chicago Union Station. The journey, including transfers, takes approximately 23h 49m.
St. Louis to Buffalo train services, operated by Amtrak, depart from St. Louis station.
St. Louis to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.
Book your St. Louis to Buffalo train tickets online with Omio.
The distance between St. Louis and Buffalo is 1063.3 km. The road distance is 1185 km.
You can take a train from St. Louis to Buffalo via Chicago Union Station and Buffalo Depew Station in around 17h 39m.
