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St. Louis to Framingham trains

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Trip Overview

The train between St. Louis and Framingham takes 28h 3m. There is at least one train per day from St. Louis to Framingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 3m
Duration
1,274 mi
Distance
$832
Average price
Once daily
Frequency

St. Louis to Framingham train times

Trains run once daily between St. Louis and Framingham. The service departs St. Louis at 2:55 PM in the afternoon, which arrives into Framingham at 19:58:00. All services require a transfer, and take on average 28h 3m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

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    Arrives next day

    AmtrakAmtrak28h 3m • 1 change

Departing Saturday, October 31, 2026

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    Arrives next day

    AmtrakAmtrak28h 3m • 1 change

Departing Sunday, November 1, 2026

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    Arrives next day

    AmtrakAmtrak28h 3m • 1 change

Departing Monday, November 2, 2026

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    Arrives next day

    AmtrakAmtrak28h 3m • 1 change

Departing Tuesday, November 3, 2026

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    Arrives next day

    AmtrakAmtrak28h 3m • 1 change

Departing Wednesday, November 4, 2026

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    Arrives next day

    AmtrakAmtrak28h 3m • 1 change

Departing Thursday, November 5, 2026

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    Arrives next day

    AmtrakAmtrak28h 3m • 1 change

Frequently asked questions

Want to know about travelling from St. Louis to Framingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Framingham.ExpandLaunch map view
  • Distance: 1,273.7 mi
  • Duration: 28h 3m

What companies run services between St. Louis, MO, USA and Framingham, MA, USA?

You can take a train from St. Louis to Framingham Amtrak via Chicago Union Station in around 27h 23m.

Operators