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St. Louis to Harrisburg, Pa trains

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Trip Overview

The train between St. Louis and Harrisburg, Pa takes 27h 45m. The train runs, on average, 6 times per week from St. Louis to Harrisburg, Pa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

27h 45m
Duration
1,002 mi
Distance
$652
Average price
6 times a week
Frequency

St. Louis to Harrisburg, Pa train times

Trains run 6 times a week between St. Louis and Harrisburg, Pa. The service departs St. Louis at 8:10 AM in the morning, which arrives into Harrisburg, Pa at 12:55:00. All services require a transfer at Chicago Union Station and take an average of 27h 45m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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Departing Thursday, November 5, 2026

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    AmtrakAmtrakAmtrak27h 45m • 2 changes

Departing Friday, November 6, 2026

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    Arrives next day

    AmtrakAmtrakAmtrak27h 45m • 2 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    AmtrakAmtrakAmtrak27h 45m • 2 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    AmtrakAmtrakAmtrak27h 45m • 2 changes

Departing Monday, November 9, 2026

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    Arrives next day

    AmtrakAmtrakAmtrak27h 45m • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Harrisburg, Pa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 1,001.7 mi
  • Duration: 27h 45m

What companies run services between St. Louis, MO, USA and Harrisburg, Pa, PA, USA?

You can take a train from St. Louis to Harrisburg via Chicago Union Station and Pittsburgh Amtrak Station in around 21h 45m.

Operators