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St. Louis to Irvine trains

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Trip Overview

The average train between St. Louis and Irvine takes 42h 54m and the fastest train takes 42h 30m. The train runs, on average, 5 times per week from St. Louis to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

42h 54m
Duration
2,061 mi
Distance
$589
Average price
5 times a week
Frequency

St. Louis to Irvine train times

Trains run 5 times a week between St. Louis and Irvine. The earliest departure is at 3:11 PM in the afternoon, and the last departure from St. Louis is at 3:11 PM which arrives into Irvine at 7:41 AM. All services require a transfer at Kansas City and take an average of 42h 54m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

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    Arrives +2 days

    AmtrakAmtrakMetrolink Trains44h 30m • 2 changes

Departing Saturday, October 10, 2026

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    Arrives +2 days

    AmtrakAmtrakMetrolink Trains42h 30m • 2 changes

Departing Sunday, October 11, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakMetrolink Trains42h 30m • 2 changes

Departing Monday, October 12, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakMetrolink Trains42h 30m • 2 changes

Departing Tuesday, October 13, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakMetrolink Trains42h 30m • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Irvine.ExpandLaunch map view
  • Distance: 2,060.7 mi
  • Duration: 42h 54m

What companies run services between St. Louis, MO, USA and Irvine, CA, USA?

You can take a train from St. Louis to Tustin via Kansas City, Fullerton Amtrak Station, and Fullerton in around 42h 55m.

Operators