The average train between St. Louis and La Crosse takes 11h 47m and the fastest train takes 11h 41m. The train service runs several times per day from St. Louis to La Crosse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between St. Louis and La Crosse. The earliest departure is at 4:30 AM at night, and the last departure from St. Louis is at 8:10 AM which arrives into La Crosse at 8:04 PM. All services require a transfer, and take on average 11h 47m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to La Crosse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from St. Louis to La Crosse. However, there are services departing from St. Louis station and arriving at La Crosse station via Chicago Union Station station. The journey, including transfers, takes approximately 11h 47m.
St. Louis to La Crosse train services, operated by Amtrak, depart from St. Louis station.
St. Louis to La Crosse train services, operated by Amtrak, arrive at La Crosse Amtrak Station.
Book your St. Louis to La Crosse train tickets online with Amtrak.
The distance between St. Louis and La Crosse is 581.9 km. The road distance is 902 km.
You can take a train from St. Louis to La Crosse Amtrak Station via Chicago Union Station in around 10h 54m.