The average train between St. Louis and Mendota takes 11h 37m and the fastest train takes 8h 18m. The train service runs several times per day from St. Louis to Mendota. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between St. Louis and Mendota. The earliest departure is at 6:35 AM in the morning, and the last departure from St. Louis is at 5:40 PM which arrives into Mendota at 9:04 AM. All services require a transfer, and take on average 11h 37m. The schedules shown below are for the next available departures.

8h 18m • 1 change

11h 11m • 1 change
Arrives next day

15h 24m • 1 change

8h 18m • 1 change

11h 11m • 1 change
Arrives next day

15h 24m • 1 change

8h 18m • 1 change

11h 11m • 1 change
Arrives next day

15h 24m • 1 change

8h 18m • 1 change

11h 11m • 1 change
Arrives next day

15h 24m • 1 change

8h 18m • 1 change

11h 11m • 1 change
Arrives next day

15h 24m • 1 change
Want to know about travelling from St. Louis to Mendota? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from St. Louis to Mendota. However, there are services departing from St. Louis station and arriving at Mendota station via Chicago Union Station station. The journey, including transfers, takes approximately 11h 37m.
St. Louis to Mendota train services, operated by Amtrak, depart from St. Louis station.
St. Louis to Mendota train services, operated by Amtrak, arrive at Mendota Station.
Book your St. Louis to Mendota train tickets online with Amtrak.
The distance between St. Louis and Mendota is 337.4 km. The road distance is 584 km.
You can take a train from St. Louis to Mendota Station via Chicago Union Station in around 7h 18m.