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St. Louis to Spartanburg trains

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Trip Overview

The train between St. Louis and Spartanburg takes 2d 19h. The train runs, on average, 4 times per week from St. Louis to Spartanburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 19h
Duration
1,598 mi
Distance
$1,043
Average price
4 times a week
Frequency

St. Louis to Spartanburg train times

Trains run 4 times a week between St. Louis and Spartanburg. The service departs St. Louis at 8:10 AM in the morning, which arrives into Spartanburg at 04:21:00. All services require a transfer at Chicago Union Station and take an average of 2d 19h. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +3 days

    AmtrakAmtrakAmtrakAmtrak2d 19h • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +3 days

    AmtrakAmtrakAmtrakAmtrak2d 19h • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +3 days

    AmtrakAmtrakAmtrakAmtrak2d 19h • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +3 days

    AmtrakAmtrakAmtrakAmtrak2d 19h • 3 changes

Frequently asked questions

Want to know about travelling from St. Louis to Spartanburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Spartanburg.ExpandLaunch map view
  • Distance: 1,598.4 mi
  • Duration: 2d 19h

What companies run services between St. Louis, MO, USA and Spartanburg, SC, USA?

You can take a train from St. Louis to Spartanburg Station via Chicago Union Station, Raleigh Union Station, and Charlotte Amtrak Station in around 36h 32m.

Operators