The train between St. Louis and Syracuse takes 19h 33m. There is at least one train per day from St. Louis to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between St. Louis and Syracuse. The earliest departure is at 2:55 PM in the afternoon, and the last departure from St. Louis is at 2:55 PM which arrives into Syracuse at 11:28 AM. All services require a transfer, and take on average 19h 33m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from St. Louis to Syracuse. However, there are services departing from St. Louis station and arriving at Syracuse station via Chicago Union Station station. The journey, including transfers, takes approximately 19h 33m.
St. Louis to Syracuse train services, operated by Amtrak, depart from St. Louis station.
St. Louis to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Book your St. Louis to Syracuse train tickets online with Amtrak.
The distance between St. Louis and Syracuse is 1,278.1 km. The road distance is 1,524 km.
You can take a train from St. Louis to Syracuse Regional Transportation Center via Chicago Union Station in around 18h 53m.