The average train between Stoke-on-Trent and Prestwick takes 5h 47m and the fastest train takes 5h. There is a train service every few hours from Stoke-on-Trent to Prestwick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Stoke-on-Trent and Prestwick. The earliest departure is at 6:49 AM in the morning, and the last departure from Stoke-on-Trent is at 11:59 PM which arrives into Prestwick at 10:15 AM. All services require a transfer at Manchester Piccadilly and take an average of 5h 47m. The schedules shown below are for the next available departures.



5h 23m • 3 changes



5h 19m • 3 changes



5h 9m • 3 changes



5h 25m • 3 changes



5h 25m • 3 changes



5h 27m • 3 changes



5h 17m • 3 changes



5h 25m • 3 changes



5h 25m • 3 changes



5h 24m • 3 changes



5h 50m • 3 changes



5h 25m • 3 changes
Want to know about travelling from Stoke-on-Trent to Prestwick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Stoke-on-Trent to Prestwick. However, there are services departing from Stoke-on-Trent station and arriving at Prestwick station via Manchester Piccadilly. The journey, including transfers, takes approximately 5h 47m.
Stoke-on-Trent to Prestwick train services, operated by Cross Country, depart from Stoke-on-Trent station.
Stoke-on-Trent to Prestwick train services, operated by Cross Country, arrive at Prestwick Town station.
Book your Stoke-on-Trent to Prestwick train tickets online with Cross Country, Northern Trains Limited and 4 other operators.
The distance between Stoke-on-Trent and Prestwick is 318.9 km. The road distance is 478 km.
You can take a train from Stoke-on-Trent to Prestwick Town via Manchester Piccadilly, Preston, and Glasgow Central in around 5h 28m.