The average train between Stoke-on-Trent and Slough takes 2h 37m and the fastest train takes 2h 19m. There is an hourly train service from Stoke-on-Trent to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Stoke-on-Trent and Slough. The earliest departure is at 6:49 AM in the morning, and the last departure from Stoke-on-Trent is at 10:53 PM which arrives into Slough at 6:47 AM. All services require a transfer at London Euston and take an average of 2h 37m. The schedules shown below are for the next available departures.


2h 22m • 2 changes


2h 25m • 2 changes


2h 21m • 2 changes


2h 24m • 2 changes


2h 27m • 2 changes


2h 20m • 2 changes


2h 23m • 2 changes


2h 20m • 2 changes


3h 1m • 2 changes


3h 1m • 2 changes


2h 45m • 2 changes


2h 35m • 2 changes
Want to know about travelling from Stoke-on-Trent to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Stoke-on-Trent to Slough. However, there are services departing from Stoke-on-Trent station and arriving at Slough station via London Euston. The journey, including transfers, takes approximately 2h 37m.
Stoke-on-Trent to Slough train services, operated by Avanti West Coast, depart from Stoke-on-Trent station.
Stoke-on-Trent to Slough train services, operated by Avanti West Coast, arrive at Slough station.
Book your Stoke-on-Trent to Slough train tickets online with Avanti West Coast, London Underground (Tube) and Elizabeth Line (TfL).
The distance between Stoke-on-Trent and Slough is 198.3 km. The road distance is 269 km.
You can take a train from Stoke-on-Trent to Slough via London Euston, Euston station, Tottenham Court Road station, and Tottenham Court Rd in around 2h 23m.