The average train between Strasbourg and Lyon Perrache takes 5h 46m and the fastest train takes 4h 19m. The train service runs several times per day from Strasbourg to Lyon Perrache. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Strasbourg and Lyon Perrache. The earliest departure is at 6:47 AM in the morning, and the last departure from Strasbourg is at 7:03 PM which arrives into Lyon Perrache at 11:28 PM. All services require a transfer at Lyon Part Dieu and take an average of 5h 46m. The schedules shown below are for the next available departures.


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Want to know about travelling from Strasbourg to Lyon Perrache? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Strasbourg to Lyon Perrache. However, there are services departing from Strasbourg station and arriving at Lyon Perrache station via Lyon Part Dieu. The journey, including transfers, takes approximately 5h 46m.
Strasbourg to Lyon Perrache train services, operated by TGV inOui, depart from Strasbourg station.
Strasbourg to Lyon Perrache train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
The distance between Strasbourg and Lyon Perrache is 386.8 km. The road distance is 511 km.
TGV inOui operates a train from Strasbourg to Lyon Part Dieu every 2 hours. Tickets cost €100–160 and the journey takes 3h 47m.