The St. Regis Rome to Siena Trains

The St. Regis Rome to Siena trains

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Trip Overview

The average train between The St. Regis Rome and Siena takes 3h 55m and the fastest train takes 3h 13m. The train service runs several times per day from The St. Regis Rome to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 55m
Duration: 355 km
Distance: €50
Average price: Every 2 hours
Frequency

Train

best

Take the train from Roma Termini to Firenze S.M.N.train Fr
Take the train from Firenze S.M.N. to Sienatrain Re

4h 13m

€39–76

The St. Regis Rome to Siena train times

Trains run every 2 hours between The St. Regis Rome and Siena. The earliest departure is at 6:00 AM in the morning, and the last departure from The St. Regis Rome is at 9:48 PM which arrives into Siena at 7:55 AM. All services require a transfer at Roma Termini and take an average of 3h 55m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

6:00 AM → 9:38 AM
3h 38m • 1 change
9:25 AM → 12:38 PM
3h 13m • 1 change
10:25 AM → 1:40 PM
3h 15m • 1 change
11:10 AM → 2:40 PM
3h 30m • 1 change
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Departing Wednesday, November 4, 2026

6:00 AM → 9:38 AM
3h 38m • 1 change
9:25 AM → 12:38 PM
3h 13m • 1 change
10:25 AM → 1:40 PM
3h 15m • 1 change
11:10 AM → 2:40 PM
3h 30m • 1 change
Show more

Departing Thursday, November 5, 2026

6:00 AM → 9:38 AM
3h 38m • 1 change
9:25 AM → 12:38 PM
3h 13m • 1 change
10:25 AM → 1:40 PM
3h 15m • 1 change
11:10 AM → 2:40 PM
3h 30m • 1 change
Show more

Departing Friday, November 6, 2026

6:00 AM → 9:38 AM
3h 38m • 1 change
9:25 AM → 12:38 PM
3h 13m • 1 change
10:25 AM → 1:40 PM
3h 15m • 1 change
11:10 AM → 2:40 PM
3h 30m • 1 change
Show more

Departing Saturday, November 7, 2026

6:00 AM → 9:38 AM
3h 38m • 1 change
9:25 AM → 12:38 PM
3h 13m • 1 change
10:25 AM → 1:40 PM
3h 15m • 1 change
11:10 AM → 2:40 PM
3h 30m • 1 change
Show more

Departing Sunday, November 8, 2026

6:00 AM → 9:38 AM
3h 38m • 1 change
9:25 AM → 12:38 PM
3h 13m • 1 change
10:25 AM → 1:40 PM
3h 15m • 1 change
12:10 PM → 3:37 PM
3h 27m • 1 change
Show more

Departing Monday, November 9, 2026

6:00 AM → 9:38 AM
3h 38m • 1 change
9:25 AM → 12:38 PM
3h 13m • 1 change
10:25 AM → 1:40 PM
3h 15m • 1 change
11:10 AM → 2:40 PM
3h 30m • 1 change
Show more

Frequently asked questions

Want to know about travelling from The St. Regis Rome to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.