The average train between Tortona and Rome takes 5h 17m and the fastest train takes 4h 26m. The train service runs several times per day from Tortona to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Tortona and Rome. The earliest departure is at 6:32 AM in the morning, and the last departure from Tortona is at 10:32 PM which arrives into Rome at 9:25 AM. All services require a transfer, and take on average 5h 17m. The schedules shown below are for the next available departures.

4h 28m • 1 change

4h 47m • 1 change

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5h 32m • 1 change

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5h 32m • 1 change

4h 28m • 1 change

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5h 3m • 1 change

5h 32m • 1 change

4h 28m • 1 change

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5h 3m • 1 change

5h 32m • 1 change

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5h 32m • 1 change
Want to know about travelling from Tortona to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Tortona to Rome. However, there are services departing from Tortona station and arriving at Rome station via Milano Centrale. The journey, including transfers, takes approximately 5h 17m.
Tortona to Rome train services, operated by Trenitalia, depart from Tortona station.
Tortona to Rome train services, operated by Trenitalia, arrive at Roma Termini station.
Book your Tortona to Rome train tickets online with Trenitalia, ItaloTreno and Trenitalia Intercity.
The distance between Tortona and Rome is 444.2 km. The road distance is 661 km.
You can take a train from Tortona to Roma Termini via Milano Centrale in around 4h 23m.