The average train between Toulouse and Lyon Perrache takes 6h 56m and the fastest train takes 4h 52m. The train service runs several times per day from Toulouse to Lyon Perrache. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Toulouse and Lyon Perrache. The earliest departure is at 7:37 AM in the morning, and the last departure from Toulouse is at 5:43 PM which arrives into Lyon Perrache at 5:34 AM. All services require a transfer at Lyon Part Dieu and take an average of 6h 56m. The schedules shown below are for the next available departures.


4h 57m • 2 changes

4h 52m • 2 changesArrives next day


11h 51m • 2 changes

4h 57m • 2 changes

4h 52m • 2 changesArrives next day


11h 51m • 2 changes

4h 57m • 2 changes

4h 52m • 2 changesArrives next day


13h 51m • 2 changes

4h 57m • 2 changes

4h 52m • 2 changesArrives next day


11h 51m • 2 changesWant to know about travelling from Toulouse to Lyon Perrache? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Toulouse to Lyon Perrache. However, there are services departing from Toulouse station and arriving at Lyon Perrache station via Lyon Part Dieu. The journey, including transfers, takes approximately 6h 56m.
Toulouse to Lyon Perrache train services, operated by TGV inOui, depart from Toulouse Matabiau station.
Toulouse to Lyon Perrache train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
The distance between Toulouse and Lyon Perrache is 356.7 km. The road distance is 566 km.
TGV inOui operates a train from Toulouse Matabiau to Lyon Part Dieu every 4 hours. Tickets cost €110–180 and the journey takes 4h 10m.