The average train between Toulouse and Sicily takes 46h 43m and the fastest train takes 39h 44m. There is at least one train per day from Toulouse to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Toulouse and Sicily. The earliest departure is at 7:37 AM in the morning, and the last departure from Toulouse is at 5:43 PM which arrives into Sicily at 7:29 PM. All services require a transfer at Lyon Part Dieu and take an average of 46h 43m. The schedules shown below are for the next available departures.
Arrives +2 days




44h 39m • 4 changes
Arrives +2 days




2d 1h • 4 changes
Arrives +2 days




44h 39m • 4 changes
Arrives +2 days




2d 1h • 4 changes
Want to know about travelling from Toulouse to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Toulouse to Sicily. However, there are services departing from Toulouse station and arriving at Sicily station via Lyon Part Dieu. The journey, including transfers, takes approximately 46h 43m.
Toulouse to Sicily train services, operated by TGV inOui, depart from Toulouse Matabiau station.
Toulouse to Sicily train services, operated by TGV inOui, arrive at Palermo Centrale station.
Book your Toulouse to Sicily train tickets online with TGV inOui, Trenitalia and 2 other operators.
The distance between Toulouse and Sicily is 1,262.5 km. The road distance is 2,432 km.
You can take a train from Toulouse Matabiau to Palermo Notarbartolo via Lyon Part Dieu, Milano Centrale, Roma Termini, and Palermo Centrale in around 26h 7m.