The average train between Toulouse and Siena takes 25h 29m and the fastest train takes 24h 57m. The train service runs several times per day from Toulouse to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Toulouse and Siena. The earliest departure is at 7:37 AM in the morning, and the last departure from Toulouse is at 5:43 PM which arrives into Siena at 6:40 PM. All services require a transfer at Lyon Part Dieu and take an average of 25h 29m. The schedules shown below are for the next available departures.
Arrives next day



26h 1m • 3 changes
Arrives next day



24h 57m • 3 changes
Arrives next day



26h 1m • 3 changes
Arrives next day



24h 57m • 3 changes
Arrives next day



26h 1m • 3 changes
Arrives next day



24h 57m • 3 changes
Arrives next day



26h 1m • 3 changes
Arrives next day



24h 57m • 3 changes
Want to know about travelling from Toulouse to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Toulouse to Siena. However, there are services departing from Toulouse station and arriving at Siena station via Lyon Part Dieu. The journey, including transfers, takes approximately 25h 29m.
Toulouse to Siena train services, operated by TGV inOui, depart from Toulouse Matabiau station.
Toulouse to Siena train services, operated by TGV inOui, arrive at Siena station.
Book your Toulouse to Siena train tickets online with TGV inOui, Trenitalia and Trenitalia Frecce.
The distance between Toulouse and Siena is 798.1 km. The road distance is 1,396 km.
You can take a train from Toulouse Matabiau to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 14h 45m.