The average train between Twello and Brussels takes 3h 55m and the fastest train takes 3h 6m. The train service runs several times per day from Twello to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Twello and Brussels. The earliest departure is at 6:00 AM in the morning, and the last departure from Twello is at 8:00 PM which arrives into Brussels at 8:06 AM. All services require a transfer at Apeldoorn and take an average of 3h 55m. The schedules shown below are for the next available departures.



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3h 6m • 3 changesWant to know about travelling from Twello to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Twello to Brussels. However, there are services departing from Apeldoorn station and arriving at Brussel-Zuid / Bruxelles-Midi station via Gouda station. The journey, including transfers, takes approximately 3h 55m.
Twello to Brussels train services, operated by Nederlandse Spoorwegen (NS), depart from Apeldoorn station.
Twello to Brussels train services, operated by Eurostar, arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Twello to Brussels train tickets online with Omio.
The distance between Twello and Brussels is 196.1 km. The road distance is 239 km.
You can take a train from Twello to Brussel-Zuid / Bruxelles-Midi via Apeldoorn, Gouda, and Rotterdam Centraal in around 4h.