Twickenham to Manchester Piccadilly Station Trains

Twickenham to Manchester Piccadilly Station trains

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Trip Overview

The average train between Twickenham and Manchester Piccadilly Station takes 4h 48m and the fastest train takes 4h 18m. There is a train service every few hours from Twickenham to Manchester Piccadilly Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 48m
Duration: 211 mi
Distance: £136
Average price: Hourly
Frequency

Train

best

Take the train from Twickenham to Readingtrain London Waterloo - Reading
Take the train from Reading to Manchester Piccadillytrain Bournemouth - Manchester Piccadilly / ...

5h 4m

£108–169

Twickenham to Manchester Piccadilly Station train times

Trains run hourly between Twickenham and Manchester Piccadilly Station. The earliest departure is at 12:10 AM at night, and the last departure from Twickenham is at 7:10 PM which arrives into Manchester Piccadilly Station at 12:13 AM. All services require a transfer, and take on average 4h 48m. The schedules shown below are for the next available departures.

Departing Tuesday, August 18, 2026

7:10 AM → 11:29 AM
4h 18m • 1 change
7:41 AM → 12:29 PM
4h 48m • 1 change
9:10 AM → 1:29 PM
4h 18m • 1 change
9:40 AM → 2:29 PM
4h 48m • 1 change
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Departing Wednesday, August 19, 2026

12:10 AM → 9:29 AM
9h 18m • 1 change
6:10 AM → 10:29 AM
4h 18m • 1 change
7:10 AM → 11:29 AM
4h 18m • 1 change
7:41 AM → 12:29 PM
4h 48m • 1 change
Show more

Departing Thursday, August 20, 2026

12:10 AM → 9:29 AM
9h 18m • 1 change
6:10 AM → 10:29 AM
4h 18m • 1 change
7:10 AM → 11:29 AM
4h 18m • 1 change
7:41 AM → 12:29 PM
4h 48m • 1 change
Show more

Departing Friday, August 21, 2026

12:10 AM → 9:29 AM
9h 18m • 1 change
6:10 AM → 10:29 AM
4h 18m • 1 change
7:10 AM → 11:29 AM
4h 18m • 1 change
7:41 AM → 12:29 PM
4h 48m • 1 change

Frequently asked questions

Want to know about travelling from Twickenham to Manchester Piccadilly Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.