The average train between Uxbridge and Southampton takes 1h 44m and the fastest train takes 1h 32m. There is a train service every few hours from Uxbridge to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Uxbridge and Southampton. The earliest departure is at 7:08 AM in the morning, and the last departure from Uxbridge is at 10:09 PM which arrives into Southampton at 11:42 PM. All services require a transfer, and take on average 1h 44m. The schedules shown below are for the next available departures.

1h 32m • 1 change

1h 35m • 1 change

1h 36m • 1 change

1h 34m • 1 change

1h 32m • 1 change

1h 35m • 1 change

1h 36m • 1 change

1h 34m • 1 change

1h 40m • 1 change

1h 35m • 1 change

1h 34m • 1 change

1h 33m • 1 change
Want to know about travelling from Uxbridge to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Uxbridge to Southampton. However, there are services departing from Uxbridge station and arriving at Southampton station via Reading. The journey, including transfers, takes approximately 1h 44m.
Uxbridge to Southampton train services, operated by Elizabeth Line (TfL), depart from West Drayton station.
Uxbridge to Southampton train services, operated by Elizabeth Line (TfL), arrive at Southampton Central station.
Book your Uxbridge to Southampton train tickets online with Elizabeth Line (TfL) and Cross Country.
The distance between Uxbridge and Southampton is 96.3 km. The road distance is 111 km.
You can take a train from West Drayton to Southampton Central via Reading in around 2h 7m.