The average train between Vicenza and Siena takes 4h 57m and the fastest train takes 4h 10m. There is a train service every few hours from Vicenza to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Vicenza and Siena. The earliest departure is at 5:08 AM in the morning, and the last departure from Vicenza is at 7:17 PM which arrives into Siena at 7:55 AM. All services require a transfer at Padova and take an average of 4h 57m. The schedules shown below are for the next available departures.


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4h 11m • 2 changesWant to know about travelling from Vicenza to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Vicenza to Siena. However, there are services departing from Vicenza station and arriving at Siena station via Firenze S.M.N.. The journey, including transfers, takes approximately 4h 57m.
Vicenza to Siena train services, operated by Trenitalia Frecce, depart from Padova station.
Vicenza to Siena train services, operated by Trenitalia Frecce, arrive at Siena station.
Book your Vicenza to Siena train tickets online with Trenitalia Frecce, Trenitalia and ItaloTreno.
The distance between Vicenza and Siena is 248.4 km. The road distance is 337 km.
You can take a train from Vicenza to Siena via Padova and Firenze S.M.N. in around 4h 20m.