The average train between Wayne and Buffalo takes 13h 7m and the fastest train takes 10h 46m. The train service runs several times per day from Wayne to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Wayne and Buffalo. The earliest departure is at 6:47 AM in the morning, and the last departure from Wayne is at 11:04 PM which arrives into Buffalo at 3:40 PM. All services require a transfer at 30th Street Station and take an average of 13h 7m. The schedules shown below are for the next available departures.


12h 16m • 2 changes

12h 3m • 2 changesArrives next day


16h 53m • 2 changes

12h 16m • 2 changes

12h 3m • 2 changesArrives next day


16h 53m • 2 changes

11h 2m • 2 changes

10h 46m • 2 changesArrives next day


16h 36m • 2 changes

11h 2m • 2 changes

10h 46m • 2 changesArrives next day


16h 36m • 2 changes

11h 2m • 2 changes

10h 46m • 2 changesArrives next day


16h 36m • 2 changesWant to know about travelling from Wayne to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wayne to Buffalo. However, there are services departing from Wayne station and arriving at Buffalo station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 13h 7m.
Wayne to Buffalo train services, operated by SEPTA, depart from 30th Street Station.
Wayne to Buffalo train services, operated by SEPTA, arrive at Buffalo station.
The distance between Wayne and Buffalo is 429.5 km. The road distance is 872 km.
You can take a train from Wayne to Buffalo via 30th Street Station and Ny Moynihan Train Hall At Penn Station in around 11h 55m.