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Wayne to Buffalo trains

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Trip Overview

The average train between Wayne and Buffalo takes 12h 59m and the fastest train takes 10h 38m. The train service runs several times per day from Wayne to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 59m
Duration
542 mi
Distance
$584
Average price
3 times a day
Frequency

Wayne to Buffalo train times

Trains run 3 times a day between Wayne and Buffalo. The earliest departure is at 6:47 AM in the morning, and the last departure from Wayne is at 11:04 PM which arrives into Buffalo at 3:32 PM. All services require a transfer at 30th Street Station and take an average of 12h 59m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    SEPTAAmtrakAmtrak16h 28m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    SEPTAAmtrakAmtrak10h 54m • 2 changes
  •  → 

    SEPTAAmtrak AcelaAmtrak10h 38m • 2 changes
  •  → 

    Arrives next day

    SEPTAAmtrakAmtrak16h 28m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    SEPTAAmtrakAmtrak10h 54m • 2 changes
  •  → 

    SEPTAAmtrak AcelaAmtrak10h 38m • 2 changes
  •  → 

    Arrives next day

    SEPTAAmtrakAmtrak16h 28m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    SEPTAAmtrakAmtrak12h 8m • 2 changes
  •  → 

    SEPTAAmtrakAmtrak11h 55m • 2 changes
  •  → 

    Arrives next day

    SEPTAAmtrakAmtrak16h 45m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    SEPTAAmtrakAmtrak12h 8m • 2 changes
  •  → 

    SEPTAAmtrakAmtrak11h 55m • 2 changes
  •  → 

    Arrives next day

    SEPTAAmtrakAmtrak16h 45m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    SEPTAAmtrakAmtrak10h 54m • 2 changes
  •  → 

    SEPTAAmtrak AcelaAmtrak10h 38m • 2 changes
  •  → 

    Arrives next day

    SEPTAAmtrakAmtrak16h 28m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    SEPTAAmtrakAmtrak10h 54m • 2 changes
  •  → 

    SEPTAAmtrak AcelaAmtrak10h 38m • 2 changes

Frequently asked questions

Want to know about travelling from Wayne to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Wayne to Buffalo.ExpandLaunch map view
  • Distance: 541.9 mi
  • Duration: 12h 59m

What companies run services between Wayne, PA, USA and Buffalo, NY, USA?

You can take a train from Wayne to Buffalo via 30th Street Station and Ny Moynihan Train Hall At Penn Station in around 11h 50m.

Operators