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Wetzlar to Florence trains

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Trip Overview

The train between Wetzlar and Florence takes 22h 3m. The train runs, on average, 6 times per week from Wetzlar to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 3m
Duration
1,047 km
Distance
€325
Average price
6 times a week
Frequency

Wetzlar to Florence train times

Trains run 6 times a week between Wetzlar and Florence. The service departs Wetzlar at 8:32 PM in the evening, which arrives into Florence at 18:35:00. All services require a transfer at Gießen Bahnhof and take an average of 22h 3m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Regio (DB Regional)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno22h 3m • 4 changes

Departing Wednesday, November 4, 2026

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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Regio (DB Regional)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno22h 3m • 4 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Regio (DB Regional)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno22h 3m • 4 changes

Departing Friday, November 6, 2026

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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Regio (DB Regional)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno22h 3m • 4 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Regio (DB Regional)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno22h 3m • 4 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Regio (DB Regional)Swiss Federal Railways (SBB CFF FFS)Swiss Federal Railways (SBB CFF FFS)ItaloTreno22h 3m • 4 changes

Frequently asked questions

Want to know about travelling from Wetzlar to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Wetzlar to Florence.ExpandLaunch map view
  • Distance: 1,046.9 km
  • Duration: 22h 3m

What companies run services between Wetzlar, Germany and Florence, Italy?

You can take a train from Wetzlar Bahnhof to Firenze Santa Maria Novella via Gießen Bahnhof, Frankfurt, Chiasso, and Milano Centrale in around 13h 53m.

Operators