The average train between Wetzlar and Karlovy Vary takes 11h 22m and the fastest train takes 8h 23m. There is at least one train per day from Wetzlar to Karlovy Vary. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Wetzlar and Karlovy Vary. The earliest departure is at 8:32 AM in the morning, and the last departure from Wetzlar is at 8:32 PM which arrives into Karlovy Vary at 11:31 AM. All services require a transfer at Gießen Bahnhof and take an average of 11h 22m. The schedules shown below are for the next available departures.





8h 23m • 5 changes




8h 59m • 5 changes




9h 6m • 5 changesArrives next day





16h 2m • 5 changesWant to know about travelling from Wetzlar to Karlovy Vary? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wetzlar to Karlovy Vary. However, there are services departing from Gießen Bahnhof station and arriving at Karlovy Vary station via Frankfurt station, Nürnberg Hbf station and Marktredwitz station. The journey, including transfers, takes approximately 11h 22m.
Wetzlar to Karlovy Vary train services, operated by Deutsche Bahn Regio (DB Regional), depart from Gießen Bahnhof station.
Wetzlar to Karlovy Vary train services, operated by České dráhy (ČD), arrive at Karlovy Vary station.
Book your Wetzlar to Karlovy Vary train tickets online with Omio.
The distance between Wetzlar and Karlovy Vary is 311.6 km. The road distance is 396 km.
You can take a train from Wetzlar Bahnhof to Karlovy Vary via Gießen Bahnhof, Frankfurt, Nürnberg Hbf, Marktredwitz, and Cheb in around 8h.