The average train between Wien Mitte and Prague takes 4h 30m and the fastest train takes 4h 28m. The train service runs several times per day from Wien Mitte to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Wien Mitte and Prague. The earliest departure is at 4:55 AM at night, and the last departure from Wien Mitte is at 6:55 PM which arrives into Prague at 11:32 PM. All services require a transfer, and take on average 4h 30m. The schedules shown below are for the next available departures.

4h 28m • 1 change

4h 31m • 1 change

4h 28m • 1 change

4h 28m • 1 change

4h 28m • 1 change

4h 31m • 1 change

4h 28m • 1 change

4h 28m • 1 change

4h 28m • 1 change

4h 31m • 1 change

4h 28m • 1 change

4h 28m • 1 change

4h 28m • 1 change

4h 31m • 1 change

4h 28m • 1 change

4h 28m • 1 change

4h 28m • 1 change

4h 31m • 1 change

4h 28m • 1 change

4h 28m • 1 change
Want to know about travelling from Wien Mitte to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wien Mitte to Prague. However, there are services departing from Wien Mitte station and arriving at Prague station via Praha Hlavni Nadrazi. The journey, including transfers, takes approximately 4h 30m.
Wien Mitte to Prague train services, operated by ÖBB, depart from Wien Hbf station.
Wien Mitte to Prague train services, operated by ÖBB, arrive at Praha Hlavni Nadrazi station.
The distance between Wien Mitte and Prague is 253.4 km. The road distance is 404 km.
Railjet operates a train from Wien Hbf to Praha Hlavni Nadrazi hourly. Tickets cost Kč 1,300–2,100 and the journey takes 4h 13m. RegioJet also services this route every 4 hours.