The average train between Wuppertal and Brussels takes 4h 8m and the fastest train takes 3h 38m. There is a train service every few hours from Wuppertal to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Wuppertal and Brussels. The earliest departure is at 6:57 AM in the morning, and the last departure from Wuppertal is at 10:57 PM which arrives into Brussels at 8:35 AM. All services require a transfer, and take on average 4h 8m. The schedules shown below are for the next available departures.

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3h 38m • 1 changeWant to know about travelling from Wuppertal to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wuppertal to Brussels. However, there are services departing from Wuppertal station and arriving at Brussels station via Aachen Hbf. The journey, including transfers, takes approximately 4h 8m.
Wuppertal to Brussels train services, operated by National Express, depart from Wuppertal Hbf station.
Wuppertal to Brussels train services, operated by National Express, arrive at Bruxelles Midi station.
Book your Wuppertal to Brussels train tickets online with National Express, Eurostar and Deutsche Bahn Intercity (DB IC).
The distance between Wuppertal and Brussels is 200.8 km. The road distance is 266 km.
You can take a train from Wuppertal Hbf to Bruxelles Midi via Aachen, Hbf in around 3h 44m.